|
KMID : 0606019990050010077
|
|
Soonchunhyang Journal of Industrial Medicine
1999 Volume.5 No. 1 p.77 ~ p.85
|
|
|
Significance of Urinary of δ-aminolevulinic acid Measurement in the Evaluation of Renal Function in Lead Exposed Workers
|
|
Lee Byung-Kook
Lee Sook
Kim Yong-Bae
Lee Gap-Soo
Kim Hwa-Sung
Hwang Kyu-Yoon
Jang Bong-Ki
Lee Sung-Soo
Ahn Kyu-Dong
|
|
|
Abstract
|
|
|
To clarify the effect of occupational lead exposure on renal function 241 lead workers working and 56 non lead workers were studied in 5 lead acid battery industries.
Study variables for renal effect were urinary N-acetyl-β-D-glucosaminidase(NAG), urinary total protein(U-TP), blood urea nitrogen(BUN), serum creatinine(S-Cr), and serum uric acid(S-Ua). On the other hand, blood lead(PbB), zinc protoporphyrin in whole blood(ZPP), and delta-aminolevulinic acid in urine(δ-ALA) were selected for the variables of lead exposure. Information on age, work duration, smoking and drinking history were also obtained.
The results obtained were as follows.
While the mean values of lead exposure indicators of lead workers were significantly different from non-exposed ones, the mean values of BUN, U-TP and S-Cr of renal function indicators of exposed were also different from non-exposed.
BUN, U-TP and NAG showed statistically significant correlation with PbB and ZPP, and NAG revealed also statistically strongly significant correlation with δ-ALA.
On multiple regression using renal fuction indicators as a dependent variable and δ-ALA, age, work duration,lead exposure,smoking and drinking as independent variables, only δ-ALA contributed to NAG.
|
|
|
KEYWORD
|
|
|
Lead exposed workers, δ - ALA, Evaluation of renal function
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|